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Researchers administered intravenous DSIP to insomnia patients over several days and conducted polysomnographic sleep studies to objectively measure sleep architecture changes including time to sleep onset, total sleep time, and sleep stage distribution

Cell-culture (in-vitro) time courses in the literature In dermal-fibroblast and keratinocyte culture studies, the published literature reports observable changes in gene-expression profiles within hours of GHK-Cu exposure, with collagen-related transcript changes typically described over one to seven days