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Next-Generation Oral Small-Molecule GLP-1s Unlocking Primary-Care and Emerging-Market Volume Orforglipron, GSBR-1290, and VK2735 demonstrated double-digit weight-loss efficacy in Phase 2 studies without injection-related barriers, attracting strong interest from primary-care physicians

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Data synthesis and analysis All included studies were discussed as part of the quantitative analysis

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Prescription peptide medicines such as semaglutide or tirzepatide must only be used under medical supervision

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