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Rapid Weight Loss Can Lead to Loss of Muscle Mass. UCLA Health Newsroom, 1 May 2024, SanchisGomar, Fabian, Ian J

Wang Y, Xue Y, Xu H, Zhu Q, Qin K, He Z, Huang A, Mu M, Tao X (2025) Pediococcus acidilactici Y01 reduces HFD-induced obesity via altering gut microbiota and metabolomic profiles and modulating adipose tissue macrophage M1/M2 polarization

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This is the point where most clinicians evaluate whether to continue, switch approaches, or cycle off