Limitations Although LGE is useful for reproducible assessment of myocardial scarring and replacement fibrosis, it is limited in its accuracy in the assessment of diffuse fibrosis
Yet, for surgery candidates, integrate GLP-1s as bridges, not barriersmonitor progress rigorously to avoid cost traps
Semaglutide, on the other hand, is over 4000 Daltons and is unlikely to be absorbed through the skin 7
Both are indicated for glycemic control in adults with type 2 diabetes and for reducing the risk of major adverse cardiovascular events in adults with type 2 diabetes at high risk
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while some studies report direct hepatocyte GLP-1R signaling (Shantaram et al., 2025